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Anti-NLK antibody
| 英文名称 | NLK |
| 中文名称 | 尼莫样激酶单克隆抗体 |
| 别 名 | DKFZp761G1211; FLJ21033; LAK1; Nemo like kinase; Nemo-like kinase; NLK_HUMAN; Protein LAK1; Serine/threonine protein kinase NLK; Serine/threonine-protein kinase NLK. |
DATASHEET
Host:Mouse
Target Protein:NLK
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG2a
Entrez Gene:51701
Swiss Prot:Q9UBE8
Source:Recombinant human NLK:
Purification:affinity purified by Protein G
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Nemo-like kinase (NLK) plays a role in cell fate determination and is required for differentiation of bone marrow stromal cells. It acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. It may suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. (referenced from swissprot)
Size:100ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
Cross Reactive Species:Human
Mouse
Rat
.
For research use only. Not intended for diagnostic or therapeutic use.